Symptoms of ovarian hyperstimulation syndrome

Symptoms of ovarian hyperstimulation syndrome mainly include abdominal distension, nausea and vomiting, decreased urine output, difficulty breathing, and enlarged ovaries. Ovarian hyperstimulation syndrome is usually related to the use of ovulation induction drugs, polycystic ovary syndrome, pregnancy and other factors, and requires prompt medical treatment.

1. Abdominal bloating

Abdominal bloating is an early sign of ovarian hyperstimulation syndrome, a feeling of abdominal pressure caused by enlarged ovaries and accumulation of fluid in the abdominal cavity. Patients may experience abdominal tightness or mild pain, which can be relieved by taking a semi-recumbent position and avoiding strenuous exercise. If the abdominal distension continues to worsen or abdominal distension occurs, you need to be alert to severe abdominal effusion and seek medical attention immediately.

2. Nausea and vomiting

Nausea and vomiting are often caused by abnormally elevated hormone levels in the body or increased abdominal pressure that stimulates the gastrointestinal tract. Patients may suffer from loss of appetite. It is recommended to eat small meals frequently and choose light and easy-to-digest foods. If frequent vomiting leads to dehydration, intravenous fluid rehydration treatment, such as glucose and sodium chloride injection, is required.

3. Reduced urine output

Decreased urine output indicates possible hemoconcentration or abnormal renal function, which is related to increased vascular permeability and extravasation of body fluids. Patients need to record daily urine output, maintain fluid intake, and use human albumin to correct hypoalbuminemia when necessary. Severe oliguria or anuria requires urgent medical intervention.

4. Difficulty breathing

Dyspnea is often caused by pleural effusion or large amounts of abdominal effusion compressing the lungs, and is a severe symptom. Patients may experience shortness of breath and decreased blood oxygen saturation, and require immediate oxygen and hospitalization, such as thoracentesis and drainage to relieve symptoms and monitor electrolyte balance.

5. Ovarian enlargement

Ovarian enlargement is the pathological basis. Ultrasound examination shows that the diameter of the ovary exceeds 5 cm and the number of vesicles on the surface increases. Mild enlargement requires bed rest to avoid ovarian torsion ； If the diameter of the ovary exceeds 10 cm or rupture and bleeding occur, surgical intervention such as ovarian cyst removal is required.

Patients with ovarian hyperstimulation syndrome should monitor changes in weight and abdominal circumference daily and limit high-salt diet to reduce fluid retention. Get enough rest and avoid sudden changes in position. If you receive ovulation induction treatment, you need to strictly follow the doctor's instructions to review hormone levels and ultrasound. When pre-thrombotic symptoms such as dizziness, palpitations, or lower limb edema occur, the doctor should be promptly notified to evaluate the necessity of anticoagulation therapy.