Is pregnancy with polycystic ovaries prone to miscarriage?

The probability of miscarriage after pregnancy in patients with polycystic ovary syndrome is slightly higher than that in the general population, but the risk can be significantly reduced through standardized management. Polycystic ovary syndrome may increase the risk of miscarriage due to factors such as endocrine disorders, insulin resistance, abnormal follicle development, etc., and requires comprehensive prevention and control through pre-pregnancy conditioning, pregnancy monitoring, and drug intervention.

Patients with polycystic ovary syndrome are often accompanied by hyperandrogenism and insulin resistance, two pathological conditions that may interfere with embryo implantation and placental formation. High androgen levels can alter endometrial receptivity, and insulin resistance may trigger endothelial dysfunction, both of which increase the risk of early pregnancy loss. Metformin sustained-release tablets are commonly used clinically to improve insulin sensitivity, dydrogesterone tablets regulate luteal function, and aspirin enteric-coated tablets improve uterine blood flow. These drugs need to be used under the guidance of a doctor. Regular monitoring of progesterone and HCG levels and ultrasound examinations are critical to detecting abnormalities in a timely manner.

Patients with oligoovulation may face the problem of insufficient follicular development, and the quality of the eggs produced may be poor, which may lead to chromosomal abnormalities in the fertilized eggs. In this case, it is recommended to carry out lifestyle intervention 3-6 months before pregnancy, including controlling weight to below BMI24, supplementing folic acid tablets, vitamin E soft capsules and other nutrients. For patients with thyroid dysfunction, the dose of levothyroxine sodium tablets needs to be adjusted simultaneously to maintain TSH below 2.5mIU/L. When ultrasound shows that the thickness of the endometrium is less than 8mm, estrogen patches can be used to promote endometrial growth.

It is recommended to establish a regular schedule 3 months before pregnancy and perform 150 minutes of moderate-intensity exercise such as swimming or brisk walking every week. The diet adopts a low-glycemic index model, with a daily intake of no less than 60 grams of high-quality protein, with priority given to deep-sea fish and soy products. Review hormone levels and fetal development every 2-4 weeks during pregnancy. If vaginal bleeding or abdominal pain occurs, seek medical attention immediately. Keep the perineum clean and dry, avoid bathing in the bath and strenuous exercise, and sleep on the left side to improve blood supply to the uterus.