Can I still get pregnant with reduced ovarian reserve?

With reduced ovarian reserve, there is still a chance of pregnancy before menopause, but the probability of spontaneous conception will decrease with the deterioration of reserve function. Decreased ovarian reserve function may be related to factors such as age, genetic factors, ovarian surgery, autoimmune diseases, and history of radiotherapy and chemotherapy. The clinical manifestations include shortened menstrual cycles, reduced menstrual volume, and elevated follicle-stimulating hormone levels.

When ovarian reserve is reduced but you are still ovulating, you can try to conceive naturally by monitoring the ovulation period. At this time, the remaining antral follicles in the ovary can still mature. If the receptivity of the endometrium remains normal, the chance of embryo implantation will still exist. It is recommended to monitor the development of follicles through ultrasound, and use basal body temperature measurement and ovulation test strips to accurately grasp the conception time window. It is necessary to maintain a regular schedule in life, appropriately supplement antioxidants such as coenzyme Q10 and vitamin E, and avoid exposure to endocrine disruptors in the environment.

When ovarian reserve is severely reduced with persistent anovulation, assisted reproductive technology is often required. When the anti-Mullerian hormone is less than 1.1ng/ml or the basic number of antral follicles is less than 5, a minimal stimulation program can be considered to induce ovulation. Those who have a poor response to ovulation induction drugs may need to use donor egg in vitro fertilization technology. At this time, it is necessary to comprehensively evaluate the endometrium condition, and perform hysteroscopy if necessary to rule out factors such as endometritis or intrauterine adhesions that may affect embryo implantation.

It is recommended to visit the reproductive medicine department as soon as possible to complete relevant examinations, including six sex hormones, anti-Mullerian hormone testing, thyroid function, etc. During the treatment, it is necessary to maintain emotional stability, reasonably control the body mass index between 18.5-24, and ensure 30 minutes of moderate-intensity exercise every day. Increase the intake of deep-sea fish and nuts in the diet, and if necessary, supplement dehydroepiandrosterone and other drugs to improve ovarian function under the guidance of a doctor.